Human Tracheal Epithelial Cells (HTEpC)
Primary Human Tracheal Epithelial Cells isolated from surface epithelium of human trachea.
Primary Human Tracheal Epithelial Cells (HTEpC) are isolated from the surface epithelium of human trachea and stain positive for cytokeratin.
The respiratory epithelia are responsible for the lubrication of the lungs, the maintenance of humidity, and the cleaning of the respiratory tract. They are an important target for drugs, toxins, and carcinogens. In addition, they are involved in many diseases such as cystic fibrosis. Consequently, HTEpC are useful for investigating the function and pathology of the respiratory system.
- Cryopreserved: Cryogenic vial containing 500.000 viable cells.
- Proliferating: >500.000 viable cells shipped in growth medium (T25 flask).
- Cell pellet: 1 million cells dissolved in 200µl RNAlater© for subsequent RNA, DNA or protein analysis. Cell pellets cannot be revived.
|Recommended Plating Density||10.000 – 15.000 cells per cm2|
|Passage After Thawing||P2|
|Tested Markers||cytokeratin positive|
|Guaranteed Population Doubling||> 15|
|Guaranteed Population Doublings||> 15|
Technical Library (1)
What is the precise localization for a) HNEpC, b) HTEpC, c) HBEpC, and d) HSAEpC?
a) HNEpC (Human Nasal Epithelial Cells) are isolated from nasal mucosa
b) HTEpC (Human Tracheal Epithelial Cells) from the surface epithelium of trachea
c) HBEpC from the surface epithelium of bronchie, and
d) HSAEpC (Human Small Airway Epithelial Cells) from the distal portion of the respiratory tract in the 1 mm bronchiole area (comprising the cells from bronchioli and alveoli).
Related Links and Documents
- What is the precise localization for a) HNEpC, b) HTEpC, c) HBEpC, and d) HSAEpC?
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Reference Literature (5)
Cigarette smoking increases bronchial mucosal IL-17A expression in asthmatics, which acts in concert with environmental aeroallergens to engender neutrophilic inflammation
Siew et al.; Clin Exp Allergy. 2017 Jun;47(6):740-750
Recurrent CDK1 overexpression in laryngeal squamous cell carcinoma
Bednarek et al.; Tumour Biol. 2016 Aug;37(8):11115-26
Disease-associated Neisseria meningitidis isolates inhibit wound repair in respiratory epithelial cells in a Type IV pili-independent manner
Ren and MacKichan; Infect Immun. 2014 Dec;82(12):5023-34
Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1
Takeda et al.; EMBO J. 2014 Jun 28. pii: e201487808. [Epub ahead of print]
NGF is an essential survival factor for bronchial epithelial cells during respiratory syncytial virus infection
Othumpangat et al.; PLoS One. 2009 Jul 31;4(7):e6444
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