Human Cardiac Fibroblasts (HCF)

Primary Human Cardiac Fibroblasts isolated from the ventricles of the adult heart.

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Primary Human Cardiac Fibroblasts (HCF) are isolated from the ventricles of the adult heart. They play a central role in the maintenance of the extracellular matrix in the normal heart and the synthesis of growth factors and cytokines. Under pathophysiological conditions, cardiac fibroblasts are involved in scar formation after myocardial infarction, cardiac fibrosis, and cardiac hypertrophy. HCF can be used to study such processes in vitro.

Recommended Plating Density 3.500 – 7.000 cells per cm2
Passage After Thawing P2
Tested Markers CD90 positive, smooth muscle α-actinin negative, slow muscle myosin negative
Guaranteed Population Doublings > 15
Figure 1. Human Cardiac Fibroblast Culture in phase contrast.

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