Human Tracheal Smooth Muscle Cells (HTSMC)

Primary Human Tracheal Smooth Muscle Cells (HTSMC) are isolated from the trachea from single donors and stain positive for smooth muscle α-actin. They connect the endings of the tracheal cartilage by a contractile bridge called the paries membranaceus and consequently regulate the airway lumen. Under pathological conditions like asthma, the amount of smooth muscle cells in the trachea walls is increased leading to smooth muscle hypertrophy or hyperplasia. Hence, HTSMC are suitable for in vitro studies of asthma and other pulmonary diseases.

Figure: Cross section through the trachea with c-shaped cartilage connected by the tracheal muscles.

Recommended media & reagents

References, Questions & Answers

Product Name Size Catalog Number Information Prices
Human Tracheal Smooth Muscle Cells (HTSMC) 500,000 cryopreserved cells C-12565 click to select country
Human Tracheal Smooth Muscle Cells (HTSMC) 500,000 proliferating cells C-12566 click to select country
HTSMC Pellet 1x106 cells in RNAlater C-14056 click to select country