Human Small Airway Epithelial Cells (HSAEpC)
Primary Human Small Airway Epithelial Cells isolated from the human distal respiratory tract.
Primary Human Small Airway Epithelial Cells (HSAEpC) are isolated from the distal portion of the human respiratory tract in the 1 mm bronchiole area. They stain positive for cytokeratin.
The distal respiratory tract mainly consists of pulmonary alveoli, which are spherical outcroppings of the respiratory bronchioles and are the primary sites of gas exchange with the blood. HSAEpC are qualified for functional studies to investigate disorders such as asthma or pulmonary inflammation.
- Cryopreserved: Cryogenic vial containing 500.000 viable cells.
- Proliferating: >500.000 viable cells shipped in growth medium (T25 flask).
- Cell pellet: 1 million cells dissolved in 200µl RNAlater© for subsequent RNA, DNA or protein analysis. Cell pellets cannot be revived.
|Recommended Plating Density||10.000 – 15.000 cells per cm2|
|Passage After Thawing||P2|
|Tested Markers||cytokeratin positive|
|Guaranteed Population Doubling||> 15|
|Guaranteed Population Doublings||> 15|
Technical Library (1)
What is the precise localization for a) HNEpC, b) HTEpC, c) HBEpC, and d) HSAEpC?
a) HNEpC (Human Nasal Epithelial Cells) are isolated from nasal mucosa
b) HTEpC (Human Tracheal Epithelial Cells) from the surface epithelium of trachea
c) HBEpC from the surface epithelium of bronchie, and
d) HSAEpC (Human Small Airway Epithelial Cells) from the distal portion of the respiratory tract in the 1 mm bronchiole area (comprising the cells from bronchioli and alveoli).
Related Links and Documents
- What is the precise localization for a) HNEpC, b) HTEpC, c) HBEpC, and d) HSAEpC?
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Reference Literature (7)
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DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity
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miR-146a regulates mechanotransduction and pressure-induced inflammation in small airway epithelium
Huang et al.; FASEB J. 2012 Aug;26(8):3351-64
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