Human Small Airway Epithelial Cells (HSAEpC)
Primary Human Small Airway Epithelial Cells isolated from the human distal respiratory tract.
Primary Human Small Airway Epithelial Cells (HSAEpC) are isolated from the distal portion of the human respiratory tract in the 1 mm bronchiole area. They stain positive for cytokeratin.
The distal respiratory tract mainly consists of pulmonary alveoli, which are spherical outcroppings of the respiratory bronchioles and are the primary sites of gas exchange with the blood. HSAEpC are qualified for functional studies to investigate disorders such as asthma or pulmonary inflammation.
- Cryopreserved: Cryogenic vial containing 500.000 viable cells.
- Proliferating: >500.000 viable cells shipped in growth medium (T25 flask).
- Cell pellet: 1 million cells dissolved in 200µl RNAlater© for subsequent RNA, DNA or protein analysis. Cell pellets cannot be revived.
|Recommended plating density||10,000 – 15,000 cells per cm2|
|Passage After Thawing||P2|
|Tested Markers||cytokeratin positive|
|Guaranteed Population Doubling||> 15|
Technical Library (1)
What is the precise localization for a) HNEpC, b) HTEpC, c) HBEpC, and d) HSAEpC?
a) HNEpC (Human Nasal Epithelial Cells) are isolated from nasal mucosa
b) HTEpC (Human Tracheal Epithelial Cells) from the surface epithelium of trachea
c) HBEpC from the surface epithelium of bronchie, and
d) HSAEpC (Human Small Airway Epithelial Cells) from the distal portion of the respiratory tract in the 1 mm bronchiole area (comprising the cells from bronchioli and alveoli).
Related Links and Documents
- What is the precise localization for a) HNEpC, b) HTEpC, c) HBEpC, and d) HSAEpC?
Application Notes (0)
Sorry, there are no results for "HSAEpC" in Application Notes.
Reference Literature (7)
The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo
Hyun et al.; Glycobiology. 2016 Aug;26(8):834-49
Down-regulation of thioredoxin1 is involved in death of Calu-6 lung cancer cells treated with suberoyl bishydroxamic acid
You et al.; J Cell Biochem. 2016 May;117(5):1250-61
PX-12 induces apoptosis in Calu-6 cells in an oxidative stress-dependent manner
You et al.; Tumour Biol. 2015 Mar;36(3):2087-95
Influence of airway wall compliance on epithelial cell injury and adhesion during interfacial flows
Higuita-Castro et al.; J Appl Physiol (1985). 2014 Dec 1;117(11):1231-42
DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity
van Jaarsveld et al.; Mol Oncol. 2014 May;8(3):458-68
Toxicological effects of PM0.25-2.0 particles collected from a photocopy center in three human cell lines
Khatri et al.; Inhal Toxicol. 2013 Sep;25(11):621-32
miR-146a regulates mechanotransduction and pressure-induced inflammation in small airway epithelium
Huang et al.; FASEB J. 2012 Aug;26(8):3351-64
- Posters (1)
Sorry, there are no results for "HSAEpC" in Brochures.
Sorry, there are no results for "HSAEpC" in FAQs.