Human Follicle Dermal Papilla Cells (HFDPC)

Primary Human Follicle Dermal Papilla Cells isolated from human dermis of the scalp, originating from the occipital or temple region.

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Primary Human Follicle Dermal Papilla Cells (HFDPC) are isolated mainly from human dermis of the scalp, originating from the occipital or temple region. Information on donor hair and skin color is available on request. HFDPC stain positive for alkaline phosphatase.

Dermal papillae are embedded in a laminin and collagen IV rich extracellular matrix at the base of the hair follicles. They are essential for the induction and maintenance of hair growth. Since they have androgen receptors, they can be used for in vitro screening of androgen blocking reagents.

Available formats:

  • Cryopreserved: Cryogenic vial containing 500.000 viable cells.
  • Proliferating: >500.000 viable cells shipped in growth medium (T25 flask).
  • Cell pellet: 1 million cells dissolved in 200µl RNAlater© for subsequent RNA, DNA or protein analysis. Cell pellets cannot be revived.
Recommended Plating Density 5.000 – 10.000 cells per cm2
Passage After Thawing P2
Tested Markers Alkaline phosphates positive
Guaranteed Population Doubling > 10
Guaranteed Population Doublings > 10
Figure 1. Human Follicle Dermal Pipilla Cell Culture in pahse contrast
Figure 2. Diagram showing the location of the dermal papilla in the hair follicle.

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