Beta-Secretase Inhibitor II

A potent, cell permeable, and reversible inhibitor of beta-secretase.

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Beta-Secretase Inhibitor II
PK-CA577-7502-1
  1 mg
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A potent, cell permeable, and reversible inhibitor of β-secretase that corresponds to the βsecretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Aβtotal (IC50 = 700 nM) and Aβ1-42 (IC50 = 2.5 μM) in CHO cells stably transfected with wild-type APP751.