β-Secretase Inhibitor Screening Kit

Highly sensitive, high throughput-compatible fluorometric assay for screening potential BACE1 inhibitors.

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β-Secretase Inhibitor Screening Kit
PK-CA577-K720
  100 assays
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In the β-Secretase Inhibitor Screening Kit, human BACE1 cleaves a quenched substrate, specific for BACE1, generating a product with high fluorescence that can be measured at Ex/Em= 435/500 nm. In the presence of BACE1 Inhibitor (a control is included in this kit), the enzymatic cleavage is impeded. The assay can be used to screen for new inhibitor compounds. It is high-throughput adaptable and can be completed in less than 1 hour.