Induces DNA single strand breaks and apoptosis e.g. in HeLaS3 tumor cells
An apoptosis inducer and a mouse STING ligand.
Anti-tumor antibiotic that induces apoptosis; Apoptosis Inducer & Topoisomerase Inhibitor
An inhibitor of XIAP (X-linked inhibitor-of-apoptosis protein).
Induces apoptosis e.g. in human T cells, mouse thymocytes, and HL-60 human leukemia cells; Apoptosis Inducer & Topoisomerase Inhibitor.
Ready-to-use apoptosis inducer & Topoisomerase Inhibitor.
A cell-permeable, fluorogenic, cationic, lipophilic mitochondrial toxin..
A caspase activator and apoptosis inducer.
A potent small molecule antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.
Produces cell cycle arrest and apoptosis (>99% pure). Apoptosis Inducer & Protein Tyrosine Kinase Inhibitor
Useful in cell activation experiments when calcium dose-response data are not required (>90% pure)
Useful for studies of Ca2 transport across biological membranes and measurement of cytoplasmic free Ca2 ; induces apoptosis.
1-N-[2-(1H-indol-3-yl)ethyl]-4-N-pyridin-4-ylbenzene-1,4-diamine; Serdemetan; A novel HDM2 (Human Double Minute-2) antagonist.
3,4',5,7-Tetrahydroxyflavone, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Robigenin
A SMAC mimetic and inhibitor of multiple IAPs (i.e. XIAP, c-IAP).
A potent anti-tumor agent, which causes growth arrest and apoptosis of a variety of human solid tumors in vitro and in vivo.
Inhibitor of DNA synthesis, nuclear division. Induces apoptosis in cancer cells.
Apoptosis Inducer & Phosphatase Inhibitor; induces apoptosis e.g. in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells.
Phospholipid structurally similar to Sphingosine that induces apoptosis in human T-cell lymphoma and non-small cell lung cancer cells.
A rapid inducer of apoptosis (10 mM solution).
Induces apoptosis in various cells, e.g. in vascular smooth muscle cells
Potent apoptosis inducer & Protein Kinase C Inhibitor
Induces apoptosis e.g. in human malignant glioma cell lines. Apoptosis Inducer & Protein Kinase C Inhibitor
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