An important cholesterol metabolite that has been shown to induce cell death in neuroblastoma cells, possibly via a necroptosis pathway.
Potent inducer of apoptosis in many cell lines
Ready-to-use apoptosis inducer
Activator of p54 and MAP kinases; induces apoptosis e.g. in the human monoblastoid cell line
Apoptosis activator that promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome.
Contains 5 ready-to-use apoptosis inducers (Actinomycin D, Camptothecin, Cycloheximide, Dexamethasone, Etoposide) in a kit format
AT-101 acts as an inhibitor of the anti-apoptotic Bcl proteins and an inducer of the pro-apoptotic proteins Noxa and Puma.
3-Methyl-1-(4-phenyl-2-thiazolyl)-1?H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]; BAM7
An isoquinoline alkaloid acts as an anti-cancer agent, inhibits cell growth and induces apoptosis in a variety of cancer cell lines.
Anti-tumor and anti-HIV agent that induces apoptosis
A potent and selective death receptor 5 (DR5) activator.
TL32711; A SMAC mimetic and IAP antagonist.
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