Monocytes 

Monocytes (Mo) are immature phagocytic cells circulating in the blood. Acting as antigen-presenting immune cells, they can phagocytize and degrade microbes and particulate matter. Monocytes can differentiate into several different cell types. The most common applications for Monocytes are the in vitro differentiation into monocyte-derived dendritic cells (moDC), macrophages, and osteoclasts as well as their use as phagocytic immune cells in immunology and infection biology.

CD14 belongs to the family of LPS receptor antigens and is strongly expressed on the majority of Monocytes. Thus, binding of immunomagnetic particles to this antigen is employed for purification of PromoCell CD14⁺-Monocytes (hMoCD14⁺-PB) from Mononuclear Cells (MNC).
In contrast, the “untouched” Monocytes (hMo-PB) provided by PromoCell are enriched from MNC by a density gradient-based method completely devoid of using any immunomagnetic beads. The advantage of these completely native Monocytes is that potential effects of bound magnetic particles (which can be ingested by this phagocytic cell type)  are excluded.

• Human CD14⁺ Monocytes (hMoCD14⁺-PB)
• Human Monocytes (hMo-PB)