Applications
- Bone differentiation
- Bone remodeling
- Bone physiology research
- Oncology
- Inflammatory studies
Features
- Alkaline phosphatase positive
- Tested for mineralization
- Available from knee and hip femoral tissue
- Cryopreserved at second passage
Osteoblasts
Human Osteoblasts (HOB) are isolated from normal femoral bone tissue from the knee and the hip joint region (lot specific source information is available on request). They stain positive for alkaline phosphatase and can be mineralized using PromoCell Mineralization Medium.
Osteoblasts are mononuclear cells of mesenchymal origin and are mainly responsible for bone formation and remodeling. In vivo, they produce a calcificated and collagen type I rich extracellular matrix called the osteoid.
During their development, osteoblasts undergo a maturation process called osteogenesis. When they become encased in the bone matrix, they stop proliferating and become osteocytes.
Recommended products
Related products
PromoCell Academy Training Courses
- Osteoblasten und Chondrozyten (German)
Knowledge Base
To view literature references for this product, please click here.To view questions and answers for this product, please click here.
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