Applications
- Hair growth research
- Drug testing
- Toxicological testing
Features
- Alkaline phosphatase positive
- Cryopreserved at second passage
- Available from adult lateral scalp
- Available from donors with different hair colors
Follicle Dermal Papilla Cells
Human Follicle Dermal Papilla Cells (HFDPC) are isolated from human dermis originating from the lateral scalp. Information on donor hair and skin color is available for each lot. HFDPC stain positive for alkaline phosphatase.
Dermal papillae are embedded in a laminin and collagen IV rich extracellular matrix at the base of the hair follicles. They are essential for the induction and maintenance of hair growth. Since they have androgen receptors, they can be used for in vitro screening of androgen blocking reagents.
The cells have been tested: Alkaline phosphatase positive
Figure: Diagram showing the location of the dermal papilla in the hair follicle.
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Knowledge Base
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