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Human Uterine Microvascular Endothelial Cells (HUtMEC)

Primary Human Uterine Microvascular Endothelial Cells (HUtMEC) are isolated from the myometrium (middle layer of the uterine wall) from a single donor who is not pre-treated with hormones. The cells are routinely analyzed by immunofluorescent staining: they stain positive for CD31 and von Willebrand factor and negative for smooth muscle alpha-actin.

During pregnancy HUtMEC propagate intensely and change their phenotype and expression pattern in response to sex steroids. This includes up-regulation of HUtMEC nitric oxide synthase activity, modulation of adhesion molecule expression, and an increase in endothelial cell survival and angiogenic activity.  HUtMEC are involved in medical conditions like uterine fibroma or adeno-mysis.

Recommended media & reagents

 Which medium should I choose? Growth Medium MV or MV2?

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References, Questions & Answers

Product Name Size Catalog Number Information Prices
Human Uterine Microvascular Endothelial Cells (HUtMEC) 500,000 cryopreserved cells C-12295 click to select country
Human Uterine Microvascular Endothelial Cells (HUtMEC) 500,000 proliferating cells C-12296 click to select country
HUtMEC Pellet 1x106 cells in RNAlater C-14028 click to select country