Applications
- Angiogenesis research
- Oncology
- Drug uptake studies
- Cell-cell junction investigation
- Inflammation studies
Features
- Von Willebrand factor (vWF) positive
- CD31 positive
- Smooth muscle alpha-actin negative
- Cryopreserved at second passage

HPMEC are isolated from the lung from a single donor. The cells are routinely analyzed by immunofluorescent staining: they stain positive for CD31 and von Willebrand factor and negative for smooth muscle alpha-actin.
The lung has a vast endothelial surface area, which is essential for the exchange of gases. HPMEC are most appropriate for studying human lung diseases.