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Human Dermal Blood Endothelial Cells (HDBEC)

Primary Human Dermal Blood Endothelial Cells (HDBEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor. (Human Dermal Lymphatic Endothelial Cells (HDLEC) from the same donor are available on request.)

The cells are routinely analyzed by flow cytometric analysis and immunofluorescent staining: they are > 95% CD31 positive and stain positive for von Willebrand factor. In addition, they are > 90% negative for podoplanin and stain negative for smooth muscle specific alpha-actin.

Blood Endothelial Cells have a key function in physiological processes like vessel tonus, capillary permeability, blood coagulation, fibrolysis, and angiogenesis. They are also useful for disease studies of atherosclerosis, tumor genesis, and thrombosis.

Figure 1: Flow cytometric analysis of PromoCell HDBEC. 98% of the cells are CD31 positive.

Figure 2: Flow cytometric analysis of PromoCell HDBEC. 91% of the cells are Podoplanin negative.

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References, Questions & Answers

Product Name Size Catalog Number Information Prices
Human Dermal Blood Endothelial Cells (HDBEC) juvenile foreskin 500,000 cryopreserved cells C-12211 click to select country
Human Dermal Blood Endothelial Cells (HDBEC) juvenile foreskin 500,000 proliferating cells C-12214 click to select country
HDBEC Pellet 1x106 cells in RNAlater C-14018 click to select country
Human Dermal Blood Endothelial Cells (HDBEC) adult donor 500,000 cryopreserved cells C-12225 click to select country
Human Dermal Blood Endothelial Cells (HDBEC) adult donor 500,000 proliferating cells C-12226 click to select country
HDBEC adult Pellet 1x106 cells in RNAlater C-14019 click to select country