Applications
- Angiogenesis research
- Atherosclerosis research
- Oncology
- Drug uptake studies
- Cell-cell junction investigation
- Inflammation studies
Features
- Von Willebrand factor (vWF) positive
- CD31 positive
- Smooth muscle alpha-actin negative

HPAEC are isolated from human pulmonary arteries (the main pulmonary artery, left and right branches). Since the pulmonary arteries carry blood from the heart to the lungs, they are the only arteries (other than umbilical arteries) that carry deoxygenated blood.