Applications
- Cardiac research
- Physiological studies
- Pharmacological studies
Features
- Adult origin
- Sarcomeric alpha -actinin positive
- Slow muscle myosin positive
- CD 90 negative
- Qualified for long-term experiments
Cardiac Myocytes
Human Cardiac Myocytes (HCM) are isolated from the ventricles of the adult heart. They stain positive for sarcomeric alpha-actinin and slow muscle myosin.
HCM are qualified for in vitro research on cardiac diseases like hypertrophy and for physiological and pharmacological studies. Unlike freshly isolated myocytes, cultured HCM can be used for long-term experiments like investigating the longterm effects of cytokines, mechanical strain, or cell-cell interactions.
The cells have been tested: Sarcomeric alpha-actinin positive, Slow muscle myosin positive, CD 90 negative
Figure: Flow cytometric analysis of PromoCell HCM. 96 % of the cells are sarcomeric α-actinin positive.
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Knowledge Base
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