Countless physical and chemical factors are known to induce distinct cellular stresses that can manifest in a cell population in a variety of ways. Oxidative stress for example, is often defined as an imbalance of pro- and antioxidants which can lead to damage of cellular lipids, proteins and DNA. This stress is known to affect various cellular functions including gene transcription, cell proliferation and differentiation and can lead to various disorders and diseases.
PromoCell supplies a wide range of highly sensitive, convenient assay kits to study oxidative stress (e.g. glutathione & NO metabolism, oxidants & anti-oxidants) and DNA damage – allowing for the analysis of mutagenic, carcinogenic and toxic effects on cells.